Leaderboard

Well, also, looking at the plugs might give some clues as to what is happening. Also, I've had very nice looking wires that were leaking spark...it doesn't always look obvious. I used to look at the engine in the dark while running, it makes it really easy to spot. Also might test the resistances on your ignition coil to see if it's gone bad. Also, I've had problems with a partially stuck PCV valve that presented similarly.

It's almost always tire pressure or a failing tire sensor. Check to make sure there are no recalls or TSB's about reprogramming the TPMS for your year/model Is there an aftermarket sensor in any of the tires? I've seen good results with aftermarket but it would be expected for them to have higher failure rates. I highly doubt this is the case but if you're speculating 80 mph is a causation and not a correlation: The only physical way I could see speed causing this is if on insanely hot roads with over pressure tires - the heat soak at 80 mph causes the pressure to just exceed the range expected by the TPMS. I think it more likely that a TPMS sensor battery is just at the cusp of failing and performing worse at those higher speeds/G forces.